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Pharmaceutical Commerce - August 2025

Despite the ongoing turmoil over tariffs, medicine costs, and FDA policy, US wholesalers are performing well.

Pharma Wholesalers: Looking for Growth

From rethinking launch price logic to implementing rebate-aware modeling and patient-first access programs, this installment explores how disciplined governance and forward-thinking models can safeguard profitability in a volatile market.

Popping the Gross-to-Net Bubble, Part V: Innovative Pricing Models

As pharma drug pricing debates heat up, the 340B program faces mounting challenges from outdated regulations, duplicate discounts, and limited transparency.

340B Litigation and the Path Toward Transparent Drug Discount Programs

. He can be reached at nsaraceno@mjhlifesciences.com.

Videos

In the first part of his video interview with Pharma Commerce Editor Nicholas Saraceno, Alex Guillen, global pharma and life sciences director at Tive, outlines the technological obstacles that lie ahead for the industry this year.

Challenges Facing Pharma Supply Chains

Articles

The latest news for pharma industry insiders.

Pharma Pulse 1/29/25: USP Calls for Pharmacists to Volunteer, Regulatory Response to Abuse-Deterrent Drugs & more

A study explores dual-enrollment in these plans—compared to other Medicare Advantage plans— impacts North Carolina’s Medicaid fee-for-service spending.

How Dual-Eligible Special Needs Plans Affect Medicaid Spending

Podcasts

Donald Prentiss discusses the value of these pharmacies, especially during shortages.

A Closer Look Into the Role of Compounding Pharmacies 

Pharma Pulse 1/28/25: Exploring Biopharma's Dealmaking Terrain, Pharmacovigilance in Digital Therapeutics & more

Known as AVT05, the Alvotech medication is a proposed biosimilar to Simponi, prescribed to treat various inflammatory conditions. 

FDA Accepts Review of Golimumab Biosimilar

In the final part of her video interview with Pharma Commerce Editor Nicholas Saraceno, Amanda Salindong, associate director of channel & distribution at Alnylam Pharmaceuticals, shares the elements that manufacturers should consider when selecting a 3PL.

Key Factors for Choosing a 3PL Provider

Pharma Pulse 1/27/25: Digital Therapeutics with Abuse-Deterrent Pain Medication, Menopause Support and Workplace Change & more

The investment not only moves along the company’s efforts in advancing clinical studies, but also opens up 700 new jobs for the Greater Toronto area. 

AstraZeneca to Financially Commit $570M Toward Global Hub Expansion in Canada

In the second part of her video interview with Pharma Commerce Editor Nicholas Saraceno, Amanda Salindong, associate director of channel & distribution at Alnylam Pharmaceuticals, describes how she supports her organization’s channel strategy.

Featured Content

Pharmaceutical Commerce - August 2025

Pharma Wholesalers: Looking for Growth

Popping the Gross-to-Net Bubble, Part V: Innovative Pricing Models

340B Litigation and the Path Toward Transparent Drug Discount Programs