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Ruth Beadle, head, global supply chain, Sanofi, discusses how digital integration, advanced planning, and sustainability goals are transforming end-to-end supply chain operations to improve scale, speed, and environmental impact.
PC: How would you define successful E2E, and what specific processes are necessary in order to achieve this?
Beadle: The first thing I’d highlight—and I mentioned this in the keynote—is that we are a company of scale and history. It’s hard to visualize that scale without digitization. We’ve moved away from Excel and connected our data through advanced planning and ERP systems. This provides visibility at scale, which is critical for our integrated business planning process that we run monthly. It helps us evaluate scenarios for new products while optimizing service, inventory, and cost.
As a healthcare company, we believe a healthy planet supports healthy people. Sustainability is a major focus for us. Like many companies, we have visible targets: we aim to be carbon neutral by 2030 and reach net zero greenhouse gas emissions by 2045. We're actively executing on these goals. Between 2019 and 2024, we've achieved a 47% reduction in Scope 1 and 2 emissions, and a 10% reduction in Scope 3 emissions.
In supply chain, that means eliminating air shipments where possible. To do that, our planning needs to be more accurate—better demand and supply forecasting—so we can shift to sea freight and increasingly use rail at scale. Of course, some life-saving drugs will still require air freight, but overall, we are pushing hard for a more sustainable supply chain.
Full Interview Summary: Sanofi is in the midst of a significant digital transformation, with the goal of becoming the first biopharma company powered by AI at scale. A major component of that vision is building a “smart supply chain”—an end-to-end, data-driven, and digitally enabled system that provides visibility from suppliers all the way to patients. This transformation has already led to measurable results, including a 12% improvement in service levels and a 14-point gain in cost-to-serve efficiency. By eliminating outdated Excel-based workflows and implementing advanced planning and ERP systems, Sanofi has increased visibility and responsiveness across its operations.
Sustainability is another major focus. Sanofi aims to be carbon neutral by 2030 and achieve net-zero greenhouse gas emissions by 2045. Compared to 2019 levels, the company has already reduced Scope 1 and 2 emissions by 47% and Scope 3 emissions by 10%. To reach these goals, Sanofi is shifting away from air freight—used only when life-saving products require it—and investing more in sea and rail transport. The company has even piloted shipments using sailing vessels to further reduce its environmental footprint.
Reflecting on the event, Beadle highlighted the value of engaging with peers across the industry. Sessions on reimagining operations and sustainability reinforced Sanofi’s direction, while also prompting her to consider how the company can continue accelerating progress and adapting in a rapidly evolving healthcare landscape
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